3:1:1 Ceramide-Dominant Science Unlock Skin Barrier Health
Trying to win the battle against sensitive skin? Not anymore. Discover the science of skin barrier repair and the 3:1:1 ceramide-dominant ratio that will transform your skin from within.
What is 3:1:1 Optimal Ceramide Science?
Scientifically Proven Ratio
Decades of research, experts discovered the perfect balance of skin lipids for repairing the skin barrier: 3 parts Ceramides, 1 part Cholesterol, and 1 part Free Fatty Acids.
Ceramide-Dominant Power
If skin barrier is a protective brick wall, then skin lipids are the “mortar”. Ceramide is the most abundant component and crucial for effective skin barrier strengthening.
Inspired by Healthy Skin
Essential skin lipids (ceramide, cholesterol and free fatty acids) are combined in an optimal 3:1:1 ceramide-dominant ratio to support and restore the lipid balance of healthy skin.
Clinically Validated Results
Extensive clinical studies demonstrate this ratio's superior effectiveness in improving skin hydration, significantly reducing transepidermal water loss (TEWL), and strengthening the skin barrier.
What is TEWL?
Ever wonder how well your skincare really works? Scientists basically measure how much moisture your skin loses with Transepidermal Water Loss (TEWL) so a Lower TEWL = better hydrated skin.
The Ceradan® 3:1:1 advantage is Clinically Proven to Lower TEWL & Boost Hydration.
Rigorous studies confirm that Ceradan®'s unique 3:1:1 ratio significantly reduces water loss (TEWL), measurably improves skin hydration, and strengthens the skin barrier.
Elevating Skin Science with Ceradan® Advanced
Taking sensitive skincare further, Ceradan® Advanced features patented active pH control technology instead. Our formulations are clinically proven to optimise skin pH, maintaining it within the ideal acidic range – your skin's natural healthy pH zone. This scientifically-backed pH balance strengthens your skin's natural defenses, promoting lasting balance and resilience.
Strengthens Skin's Natural Defence
Supports Healthy Skin Function
Enhances Barrier Resilience
A Breakthrough Emollient That Finally Delivers
Most emollients available on the market today are designed to moisturise and soothe the skin— but when it comes to lowering and maintaining a healthy skin pH, they often fall short. The main limitation lies in their lack of true buffering capacity, meaning they may temporarily influence pH but cannot sustain those benefits over time. As a result, individuals with sensitive or compromised skin barriers continue to struggle with recurring dryness, discomfort, and flare-ups.
Ceradan® Advanced Cream stands apart as a revolutionary solution. It is the ONLY emollient clinically proven to sustainably lower skin pH, thanks to its patented active pH control technology. This advanced formulation doesn’t just moisturise; it actively restores and maintains the skin’s optimal acidic environment—supporting barrier repair, enhancing resilience, and helping break the cycle of irritation.
References:
The BARRIER 2 Study Results7# - Sheffield Dermatology Research | The University of Sheffield, UK
Stronger Skin Starts Here
Ceradan® Advanced Cream is clinically proven to significantly improve skin barrier function by sustainably reducing transepidermal water loss (TEWL). Regular use of an acidifying, barrier-repair emollient helps enhance disease control in individuals with atopic dermatitis (eczema). TEWL— an indicator of skin barrier integrity—has been shown to correlate closely with skin surface pH, highlighting the importance of maintaining an optimally acidic skin environment.
References:
Andrew PV, Pinnock A, Poyner A, Brown K, Chittock J, Kay LJ, Cork MJ, Danby SG. Dermatology Ther (Heidelb). 2024;14(2):391-408.
